A discrete view on fold space
نویسندگان
چکیده
منابع مشابه
An alternative view of protein fold space.
Comparing and subsequently classifying protein structures information has received significant attention concurrent with the increase in the number of experimentally derived 3-dimensional structures. Classification schemes have focused on biological function found within protein domains and on structure classification based on topology. Here an alternative view is presented that groups substruc...
متن کاملRESEARCH ARTICLES An Alternative View of Protein Fold Space
Comparing and subsequently classifying protein structures information has received significant attention concurrent with the increase in the number of experimentally derived 3-dimensional structures. Classification schemes have focused on biological function found within protein domains and on structure classification based on topology. Here an alternative view is presented that groups substruc...
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In this paper, there are two competitors in a planar market. The first competitor, called, the leader, opens new facilities. After that, the second competitor, the follower, reacts to the leader’s action and opens r new facilities. The leader and the follower have got some facilities in advance in this market. The optimal locations for leader and follower are chosen among predefined candida...
متن کاملOn distance and similarity in fold space
Metric information on similarities and distances in fold space is essential for quantitative work in structural bioinformatics and structural biology. Here we derive a suitable metric for protein structures from the fundamental axioms of similarity. Derivation of the metric also clarifies the relationship between the interrelated concepts of distance and similarity.
متن کاملA consensus view of fold space: combining SCOP, CATH, and the Dali Domain Dictionary.
We have determined consensus protein-fold classifications on the basis of three classification methods, SCOP, CATH, and Dali. These classifications make use of different methods of defining and categorizing protein folds that lead to different views of protein-fold space. Pairwise comparisons of domains on the basis of their fold classifications show that much of the disagreement between the cl...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2008
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btn020